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Systemic endothelial dysfunction is related to the extent and severity of coronary artery disease. In general, if certain plant foods are consumed in appropriate combinations, they can provide all the essential amino acids for human nutrition, although some of them may be absent in certain plants, including lysine in cereals, rice, and corn, and methionine in legumes [ 4 ]. Tan L. It has been well documented that different factors may contribute to the gut microbiota composition and variation. Conflicts of Interest The authors declare no conflict of interest. Several factors such as infant transitions, dietary habits, age, consumption of probiotics and prebiotics, use of antibiotics, intestinal comorbidities, and even metabolic diseases may continously alter microbiota diversity and function. This can be counteracted by consuming ascorbic acid citrus, strawberries, kiwi, a component necessary for the absorption of non-heme iron [ 1, 50 ].