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Higher consumption of artificially sweetened soft drinks was associated with an increased risk of both stroke and dementia in an analysis of more than 4, participants in the Framingham Heart Study Offspring cohort, researchers found. In the observational study, those who drank at least one artificially-sweetened beverage a day were nearly three times more likely to develop ischemic stroke HR 2. However, sugary beverages weren’t tied to an increased risk of stroke or dementia — a finding the authors called “intriguing,” and one that could have been due to survival bias. He cautioned that the association between artificially sweetened drinks and stroke and dementia seen in their study does not imply causation — a point emphasized by Marion Nestle, PhD, professor of nutrition, food studies, and public health at New York University, who wasn’t involved in the study. Several other experts commented on the “controversial but inconclusive” nature of the association. This kind of data does not allow us to say that drinking [these] beverages causes dementia, or that cutting down on artificially sweetened beverages will reduce a person’s risk for dementia. Beverage intake was quantified using the Harvard semiquantitative food-frequency questionnaire at three points: cohort examinations five —, six —, and seven — Participants were then followed for more than 10 years to determine development of stroke or dementia. Notably, data collection did not distinguish between the types of artificial sweeteners used in the beverages. Pase and colleagues found that higher recent and cumulative intake of artificially sweetened soft drinks was linked to an increased risk of ischemic stroke, all-cause dementia, and Alzheimer’s dementia — even after adjustment for total caloric intake, diet quality, physical activity, and smoking status.